October 9, 1967

Bullous Myringitis and Atypical Pneumonia

Author Affiliations

Tulsa, Okla

JAMA. 1967;202(2):156. doi:10.1001/jama.1967.03130150124040

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To the Editor:—  I read with interest the recent letter of T. J. John, MD, et al (201:273, 1967) concerning the association of bullous myringitis and primary atypical pneumonia.I recently published a study in which we attempted to relate the incidence of bullous myringitis with the Eaton agent, Mycoplasma pneumoniae. In 23 cases of bullous myringitis, complement fixation tests, viral isolation techniques, throat cultures, cold and MG agglutinin tests failed to establish a causal relationship. Complement fixation tests against 21 common viral agents also failed to indicate a relationship.It is my current thought that bullous lesions are probably nonspecific manifestations of mechanical injury which may be associated with upper-respiratory tract infection. I have also been impressed with the frequent occurrence of this disease in children afflicted with allergic diseases.