Preliminary work with an extracorporeal gas-exchanging dialyzing circuit using a membrane oxygenator principle gave promising results with animals and fetal humans. Respiratory and metabolic acidosis could be corrected, and the system might be considered as an addition to, and not a substitution for, current therapeutic methods in the management of respiratory distress syndrome.
Chamberlain G, Lee HA, Ames AA. Membrane Oxygenator-Dialyzer for the NewbornA Possible Adjunct in the Management of Respiratory Distress Syndrome. JAMA. 1967;202(4):302–304. doi:10.1001/jama.1967.03130170102017