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October 23, 1967

Effect of Dialysate Temperature and Flow Rate on Peritoneal Clearance

Author Affiliations

From the Department of Surgery, Division of Urology, State University of New York, Downstate Medical Center, Brooklyn, NY. Dr. Gross is presently affiliated with Brooke General Hospital, Fort Sam Houston, Texas.

JAMA. 1967;202(4):363-365. doi:10.1001/jama.1967.03130170163035

Intermittent peritoneal dialysis was performed to observe the effect of dialysate temperature and flow rate on peritoneal clearance. At the same hourly flow rates, the dialysate heated to 37 C had a 35% greater clearance than the dialysate at 20 C. The most efficient method of dialysis with commercially available equipment is a repeated 2-liter exchange of dialysate at 37 C with no pause between inflow and outflow. This method in an average dialysate volume of 3.3 liters/hr and an average urea nitrogen clearance of 20.8 ml/min.