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April 14, 1975

Multiple Filling Defects in the Colon

Author Affiliations

From the Division of Diagnostic Radiologic Pathology, Armed Forces Institute of Pathology (MAJ Madewell), and the Department of Radiology, Walter Reed Army Medical Center (COL Reeder), Washington, DC.

JAMA. 1975;232(2):172-173. doi:10.1001/jama.1975.03250020046027


  1. [Diverticula]

  2. Familial polyposis

  3. Polyps, adenomatous

  4. Pseudopolyps of ulcerative colitis, granulomatous colitis, amebiasis

  5. Stool; foreign bodies; air bubbles; food particles; mucus


  1. Amebomas

  2. Amyloidosis

  3. Carcinomas, multiple

  4. Colitis cystica profunda

  5. Cronkhite-Canada syndrome

  6. Gardner syndrome

  7. Lipomatous polyposis

  8. Lymphoid hyperplasia

  9. Lymphoma

  10. Metastases

  11. Mucoviscidosis

  12. Neurofibromatosis; ganglioneurofibromatosis

  13. Parasites, intraluminal (ascariasis, trichuriasis)

  14. Peutz-Jeghers syndrome (hamartomatous polyps)

  15. Pneumatosis cystoides intestinalis

  16. Polyposis, juvenile

  17. Schistosomiasis

  18. Turcot syndrome (Entity in brackets may be confused roentgenographically with multiple filling defects in the colon.)

Diagnosis  Familial polyposis of the colon.

Comment  A 22-year-old man was first seen with anemia and failure to gain weight. No gastrointestinal or pulmonary symptoms were present. There was a strong family history of carcinoma of the colon. Physical examination was unremarkable. An upper gastrointestinal series, bone survey, and chest roentgenograms were normal.A barium enema (Fig 1) demonstrated