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May 24, 1971

Pathogenesis of Venous Thrombosis

JAMA. 1971;216(8):1349. doi:10.1001/jama.1971.03180340067023

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To the Editor.—  The authors wish to thank Matzger for his letter "Pathogenesis of Venous Thrombosis" (215:799, 1971). Our agreement with Matzger is complete— the problem of thromboembolism is by no means resolved. However, we do not share his opinion that this subject is cloaked in mystery. It is our firm conviction that the inability to date to control this dreaded complication in hospital patients should not be cause for despair but rather should spur us on to continuous, diligent studies and research until the ultimate conquest is achieved.In his hurried attempt to build a case, Matzger overlooked several pertinent facts.Unquestionable reduction of the venous pool of the calf (both deep and superficial veins) was repeatedly and amply demonstrated in our illustrations and fully explained under Phlebograms. Angiography while not entirely free from pitfalls is the choice tool available to us for the delineation of vascular forms