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November 27, 1967

A Community-Wide Coxsackievirus A9 Outbreak

Author Affiliations

From the Department of Preventive Medicine, State University of New York, Upstate Medical Center, Syracuse. Drs. Novack and Voth were trainees under Public Health Service training grant 5T1-AI-239. Dr. Voth is now at the University of Kansas Medical Center, Kansas City, Kan.

JAMA. 1967;202(9):862-866. doi:10.1001/jama.1967.03130220050007

Among members of 33 families, 37% had antibodies to coxsackievirus A9 before, and 93% after, an outbreak of this disease. In all, 88% of the susceptible members of this population converted, serologically. Rash was age related, being more frequent in the very young. Clinical illness was mild but expressed more often in the very young. Among 480 children less than 6 years of age who were bled in well-baby clinics after the epidemic, 58% were found to have coxsackievirus A9 antibodies. Coxsackievirus A9 was the most frequent cause of aseptic meningitis in the community during the epidemic period.