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November 27, 1967

Acute Glomerulonephritis as a Complication of Varicella

Author Affiliations

From the State University of New York, Downstate Medical Center, Brooklyn. Dr. Yuceoglu is now at the New York Medical College, NY. Dr Berkovich is a Career Scientist of the Health Research Council of the City of New York under contract 1-173.

JAMA. 1967;202(9):879-881. doi:10.1001/jama.1967.03130220067011

Three patients, one child and two adults, showed clinical and laboratory evidence of acute glomerulonephritis in association with varicella. All three had mild to moderate proteinuria and microscopic or gross hematuria prior to or with the onset of rash. In one of the patients, renal biopsy established the diagnosis of acute glomerulonephritis. The histopathologic picture seen was identical to that described for poststreptococcal disease. Renal function studies done indicate that renal disease associated with varicella may severely compromise the function of the kidney.