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August 25, 1975

Coronary Heart Disease in the Western Collaborative Group StudyFinal Follow-up Experience of 8 1/2 Years

Author Affiliations

From the Harold Brunn Institute, Mount Zion Hospital and Medical Center, San Francisco (Drs. Rosenman and Friedman), the School of Public Health, University of California, Berkeley (Dr. Brand), the Department of Behavioral Epidemiology, Boston School of Medicine, Boston (Dr. Jenkins), the Research Laboratories, St. Joseph Hospital, Burbank, Calif (Drs. Straus and Wurm). Dr. Straus is now with the Department of Pathology, Providence Hospital, Portland, Ore.

JAMA. 1975;233(8):872-877. doi:10.1001/jama.1975.03260080034016

Clinical coronary heart disease (CHD) occurred in 257 subjects during eight to nine years of follow-up (average, 8 1/2 years) in a prospective study of 39- to 59-year-old employed men. Incidence of CHD was significantly associated with parental CHD history, reported diabetes, schooling, smoking habits, overt behavior pattern, blood pressure, and serum levels of cholesterol, triglyceride, and β-lipoproteins. The type A behavior pattern was strongly related to the CHD incidence, and this association could not be explained by association of behavior pattern with any single predictive risk factor or with any combination of them.

(JAMA 233:872-877, 1975)