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September 1, 1975

Medical News

JAMA. 1975;233(9):939-947. doi:10.1001/jama.1975.03260090005001

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Ozone in smog linked to lesions in bronchioles, enzyme changes  There's a story about a fellow from Los Angeles who vacationed at a mountain resort. He appeared terribly nervous at first, and a friend asked him if he was afraid of heights."No," said the Angeleno, "I just don't trust air I can't see."Photochemical smog isn't restricted to the Los Angeles area, of course, but the region is quite smoggy during the summer. Last year, on 84 of 92 consecutive summer days, the ozone level in the California South Coast Basin was 0.2 ppm or higher.And that level, according to investigators at the California Primate Research Center, Davis, is dangerous.Donald L. Dungworth, PhD, leader of the respiratory diseases research unit at the center, told a recent seminar for science writers that chronic exposure to 0.2 ppm ozone in the ambient air caused "obvious biochemical and structural