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June 7, 1971

The Immunology of Malignant Disease

Author Affiliations

Bar-Ilan University Ramat-Gan, Israel


by Jules E. Harris and Joseph G. Sinkovics, 251 pp, with illus, $15, St. Louis: C. V. Mosby Co., 1970.

JAMA. 1971;216(10):1650. doi:10.1001/jama.1971.03180360096029

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The preface states, "This book is intended for clinicians concerned with the management of malignant disease. It is our hope that it will offer physicians a useful introduction to ideas and methods that will have increasing relevance to the investigation and treatment of cancer in man." It is doubtful that this worthwhile goal has been reached. The book must be faulted on three counts: contents, manner of presentation, and ability to serve the reader for whom it was intended. The contents do not justify the inclusive title. Rather its chapters represent reviews of selected topics: normal immune response in man and the reactions to malignant disease; some immunological aspects of animal and human tumors; immune deficiency associated with malignant tumors; suppression of immune responses in cancer patients. Considerable portions deal with extraneous subject matter. Thus, roughly two thirds of chapter 1 outline current concepts of humoral and cell-mediated immunity. More