August 2, 1971

Rubella Immunization Risk Postpartum

Author Affiliations

Bethesda, Md

JAMA. 1971;217(5):697. doi:10.1001/jama.1971.03190050153022

To the Editor.—  Several papers have appeared recently describing the use of rubella vaccines in postpartum rubella-susceptible women.1,2 Most authorities have recommended this procedure "only when the possibility of pregnancy is essentially nil."3 Since the patient is not pregnant immediately following delivery, immunization combined with contraception appears to be quite desirable. Some programs, however, have considered postpartum immunization without reference to contraceptive, since, in their opinion, pregnancy is extremely unlikely within the ensuing two-month period.To determine the risk of a second pregnancy within two months following delivery, we analyzed the data from the Collaborative Project. In this investigation, approximately 53,000 pregnant women were studied at 12 medical centers located throughout the United States. A total of 7,507 of these women had a second pregnancy during the period of the study (1959 to 1966). From the Table it can be seen that 5.6% of the women had their second pregnancy within two months