April 15, 1968

Liver Biopsy and Radioisotope Scans

Author Affiliations

Jamaica, NY

JAMA. 1968;204(3):273. doi:10.1001/jama.1968.03140160083035

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To the Editor:—  In their article on percutaneous liver biopsy (202:53, 1967), Wilber and Foulk state that the value of hepatic scintillography in "accurately delineating the site for hepatic needle biopsy in neoplastic liver lesions is not yet proved." It is our feeling that the identification of a space-occupying lesion on a radioisotope liver scan may offer some assistance in locating a specific area for biopsy.A liver scan performed after the intravenous administration of 200μc of colloidal gold Au 198 is illustrated in Fig 1. It shows several metastatic lesions. With the scan as a guide, the borders of the liver and one of the space-occupying lesions are outlined on the patient's skin (Fig 2). Since the scan is a life-size representation of the organ without distortion, the borders so outlined indicate the projections of both the liver and metastatic lesion on the skin surface.Employing this method,