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Article
May 13, 1968

ATHEROSCLEROSIS, A PROGRESSIVE DISEASE

JAMA. 1968;204(7):626-627. doi:10.1001/jama.1968.03140200066024
Abstract

There are continuing efforts to determine the most reliable methods of selection of hypertensive patients for surgical correction of occlusive diseases of the renal arteries. The complexity of this problem is evidenced by a recent study of the medical treatment of patients with atheromatous and fibromuscular stenosis of the renal arteries.1 Although hypertension could be controlled, subsequent cardiovascular complications were relatively common among individuals with atherosclerotic disease. The clinical implications of this research and related studies must be based upon adequate documentation of the natural history of renovascular hypertension.

Wollenweber, Sheps, and Davis2 observed the clinical course of 109 patients with atherosclerotic renovascular hypertension. X-ray films of all patients demonstrated characteristic features of atherosclerosis of one or both renal arteries. Follow-up observations revealed a high incidence of coexistence of atherosclerotic disease in various regions of the body. Coincidence of atherosclerosis in the brain, heart (and other viscera), and

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