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To the Editor.—
In reference to the Question and Answer relating to digitalis effect on the ECG exercise test (217:485, 1971), using a generally accepted criterion of a positive ECG response to exercise, ie, flat or downsloping ST-segment in one or more post-exercise lead, equal to or greater than 1.0 mm in magnitude, normal persons given digitalis often may show "pseudo-positive" exercise ECGs even though the control tracing reveals little or no digitalis effects on the ST-segments.Illustrative cases are reported by Kawai and Hultgren (Amer Heart J68:409, 1964). Their article contains other pertinent bibliographic references.
Bradfield JY. Digitalis Effects On Exercise Test. JAMA. 1971;217(12):1707. doi:10.1001/jama.1971.03190120073030