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June 10, 1968

Preclinical Carcinoma of the Cervix Uteri

Author Affiliations



by Malcolm Coppleson and Bevan Reid, 321 pp, 172 illus, $15, New York and Sydney: Pergamon Press, Inc., 1967.

JAMA. 1968;204(11):1012. doi:10.1001/jama.1968.03140240068032

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Two investigators from Australia, one skilled in colposcopy and clinical gynecology and the other equally knowledgeable in the basic science aspects of regeneration and preneoplastic systems, have written an outstanding text. Colposcopy is clearly and completely detailed as well as related topics such as cervical capillary angioarchitecture, cervical dysplasia, physiological squamous metaplasia, and the early detection and treatment of preclinical squamous cell carcinoma of the cervix. Devoting several chapters to laboratory studies, the authors also include the cell biology of metaplasia and the application of general cancer theory to its process, the search for mutagens, and mutagenesis and cancer. The illustrations, numerous and superior in quality, complement the text at appropriate places, and the references are pertinent and up to date.

While they question many of the interpretations placed in cells of cervical tissues studied by the ancillary diagnostic methods of exfoliative cytology and histology, the authors stress that the