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July 8, 1968

Salivary Secretion of Blood Factors in Cancer

Author Affiliations

Salt Lake City

JAMA. 1968;205(2):115. doi:10.1001/jama.1968.03140280069024

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To the Editor:—  This is a response to a paper entitled "Salivary Secretion of Blood-Group Factors in Cancer" by Krant et al (204:153, 1968).Dr. Krant has made rather Sweeping conclusions on inadequate material. Examination of Table 1, under column "lung," shows a rather startling skew in the number of sese (nonsecretory) patients listed as group O. Serologists and immunologists are aware of errors in H (O) secretion recognition with Ulex europaeus. Lea cell typing should be done to confirm the sese status. Since he shows a 34% sese here I would suspect mistyping of secretion because if no significance existed we would expect 22.7%. Under groups A, B, and AB, this does not show because they could check the secretor status with anti A or B or both to make a confirmation.Dr. Krant does not list a category of "survivors" so it is difficult to interpret