January 17, 1972

Personality Types and Coronary Artery Disease

Author Affiliations

East Cleveland, Ohio

JAMA. 1972;219(3):385. doi:10.1001/jama.1972.03190290071025

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To the Editor.—  In a recent article (217:929, 1971), Meyer Friedman and his colleagues reported a difference in growth hormone responses in 12 subjects with extreme type A behavior pattern compared with 12 subjects with type B extreme behavior pattern.They previously published similar findings with regard to serum cholesterol, triglycerides, phospholipids, and serum beta and other low-density lipoprotein lipids (169:1286-1296, 1959; 184:934-938, 1963). Available data suggest that differences in serum cholesterol only can be demonstrated in the extreme behavior pattern subtypes and are not different in the milder expressions (195:86-92, 1966); the reader gains the impression that extreme type A compared with extreme type B subjects are clearly at higher coronary risk.A 4 1/2-year follow-up report of their prospective study demonstrates that the higher incidence of coronary artery disease occurs among subjects exhibiting the milder expressions of type A behavior pattern, but not in