September 8, 1975

Thyroid Nodularity in Children

Author Affiliations

From the departments of pediatrics (Dr. Rallison) and medicine (Dr. Tyler), University of Utah College of Medicine, Salt Lake City, the Case Western Reserve University, Cleveland (Dr. Dobyns), the Mayo Clinic, Rochester, Minn (Dr. Keating), and the National Institute of Arthritis and Metabolic Diseases, Bethesda, Md (Dr. Rall).

JAMA. 1975;233(10):1069-1072. doi:10.1001/jama.1975.03260100039017

Of 5,179 school children surveyed in Utah, Nevada, and Arizona for thyroid abnormalities because of possible exposure to radiation from fallout, nodularity of the thyroid was found in 93 (1.8%). In 34, the nodularity represented lobulation associated with adolescent goiter, and in 31, thyroiditis. Two malignant neoplasms were found. In a normal childhood population in which nodularity is incidentally discovered on physical examination, the risk of nodularity being malignant is approximately 2%. Factors that favor exploration of thyroid nodules in children are discreteness, growth of the mass, singleness, and absence of other thyroid disease.

(JAMA 233:1069-1072, 1975)