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Sept 30, 1968

Prevention of Cardiac Necrosis by Amiloride

Author Affiliations

From the Institute of Experimental Medicine and Surgery, Montreal.

JAMA. 1968;206(1):103-104. doi:10.1001/jama.1968.03150010051010

Amiloride hydrochloride, a highly potent potassiumsparing agent, protects the rat against the infarcts and mortality characteristic of electrolyte-steroid cardiopathy conducive to necrosis.