To the Editor.—
Considering the racial and geographic distribution of multiple idiopathic hemorrhagic sarcoma of Kaposi, there is no reason why multiple cases should not occur in the same family. However, this has been encountered rarely. The only available sources to mention this possibility were Montgomery who stated: "Many reviews have concluded that a familial pattern is uncommon,"1 and Bluefarb who quoted Greco as reporting a "... patient [who] was a 63-year-old man [and] whose two brothers had died of the disease and a son of one of these brothers had just developed the condition."2Some interesting aspects of the cases reported are the familial occurrence, the long period of time elapsing between the onset of the eruptions in these two individuals, and the association with the parapsoriasis en plaque which might be interpreted as another piece of evidence linking Kaposi's sarcoma with the conventional lymphomas.
Report of Cases.
Epstein E. Kaposi's Sarcoma and Parapsoriasis en Plaque In Brothers. JAMA. 1972;219(11):1477–1478. doi:10.1001/jama.1972.03190370067023