Dr. Edward H. Eliscu: The patient is a 50-year-old white woman who for 30 years had experienced malaise, fever, vomiting, and non-bloody diarrhea which was recently associated with weakness. The past medical history and the family history were noncontributory. Physical examination revealed a pale woman in no distress. Abdominal examination showed nothing remarkable. Laboratory studies revealed a hemoglobin level of 10 gm/100 cc, white blood cell count of 22,000, and a temperature of 101 F (38.3 C). Results of the guaiac test on the stool on several occasions gave 2+ values and on several occasions were not positive. Sigmoidoscopy was performed and the findings were said to be characteristic of ulcerative colitis. The stool examination revealed a few pus cells and culture produced Escherichia coli. The patient was treated with intravenous fluid and improved.
Since her first episode in 1937, she had regulated her diet, eliminating roughage and spicy foods,
Eliscu EH. Colitis of Long Duration. JAMA. 1968;206(4):833-835. doi:10.1001/jama.1968.03150040045010