[Skip to Content]
[Skip to Content Landing]
October 20, 1975

Injectable Fluid Silicone TherapyHuman Morbidity and Mortality

Author Affiliations

From the Department of Plastic and Maxillofacial Surgery, Nassau County Medical Center of Stony Brook Medical School, East Meadow, NY (Drs Rubin and Richard Ellenbogen), and the Department of Medicine, Beth Israel Medical Center, Mount Sinai Medical School, New York (Dr Rita Ellenbogen).

JAMA. 1975;234(3):308-309. doi:10.1001/jama.1975.03260160056016

Four patients who had received silicone injections had the following complications: migration, hepatic disease manifested as granulomatous hepatitis (previously undescribed, to our knowledge), hypopigmentation, and death. Silicone should now be considered as a possible cause of hepatic granulomas in an appropriate host.

(JAMA 234:308-309, 1975)