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October 20, 1975

The Physiology of Disease

Author Affiliations

New Orleans

JAMA. 1975;234(3):334. doi:10.1001/jama.1975.03260160082025

Designed for the medical student who is completing his preclinical studies and who is beginning his clinical training, The Physiology of Disease will also appeal to the busy practitioner. Its authors, Roddie and Wallace, have the knack for expressing concepts of normal and disordered physiology so clearly and succinctly that the reader comes away from their text with the impression of having learned a good deal about the subject. Among the topics they treat in a particularly interesting fashion are the effects of gravity and the disorders of immunity.

Increased gravitational (g) forces may well limit man's ability to visit the larger planets. A man weighing 70 kg on earth weighs 700 kg when subjected to the 10 g forces experienced shortly after rocket launch. The problem may be mitigated if he lies transversely in the plane of gravity so that his blood does not pool in his head or