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October 28, 1968

Systemic Lupus Erythematosus Complicated by Coccidioidomycosis

Author Affiliations

From the Davis-Monthan Air Force Base Hospital, Tucson, Ariz (Drs. Berry and Shepard), and the Department of Dermatology, University of Cincinnati College of Medicine (Dr. Goldberg). Dr. Shepard is now with the Holbrook-Hill Medical Group, Tucson.

JAMA. 1968;206(5):1083-1085. doi:10.1001/jama.1968.03150050071021

In 1950 this patient was treated with cortisone acetate for acute systemic lupus erythematosus (SLE). A state of remission was obtained until June 1963 when the patient moved to Tucson, Ariz. At this time, there was a relapse of the SLE. By Sept 30, pulmonary coccidioidomycosis developed, and by February 1964 the patient manifested the disseminated form of this disease. By Dec 15, a total of 2,285 mg of amphotericin B had been administered. Both diseases have remained in remission with residuals of nephrotic syndrome, persistent anemia, and leukopenia.