April 3, 1972

Seven-Year "Cure" of Lung Cancer With Metastasis to the Brain

Author Affiliations

Danville, Pa

JAMA. 1972;220(1):127. doi:10.1001/jama.1972.03200010111029

To the Editor.—  Pulmonary resection is considered to be contraindicated in patients with carcinoma of the lung who have cerebral metastases.1 Recommendations for proper therapy of a solitary cerebral metastasis vary widely. Knight thought that both the primary and secondary growths should be excised, and found a definite prolongation of the patient's life thereby.2 Others3-6 also indicated that if the metastatic lesion is single and located in an accessible part of the brain, extirpation may result in a longer survival time, with relief of many distressing and disabling symptoms.Flavell reported a patient who was alive, well, and working ten years after resection of both the pulmonary tumor and the cerebral metastasis.7 Bakay reported five-year survival after resection of an intracranial metastasis followed by radiation therapy to the primary lesion.8 At autopsy, a huge brain cyst was found, but there was no residual tumor in