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To the Editor.—
Referring to the LETTERS of Lancaster and Roberts (217:1106, 1971), it should be remembered that high-dose antibiotic treatment of patients with known gonorrhea will not in itself alter the development of resistance to the antibiotic by the gonococcus. The real problem comes in the treatment of unknown asymptomatic women carriers with low doses of antibiotics for other infections. It is in these women that the gonococcus has the opportunity to develop resistance to the antibiotic administered. One solution to this quandary is the routine culturing for the gonococcus of all women about to undergo antibiotic treatment of any infection, which is less than practical. An alternative is to reserve an antibiotic exclusively for the treatment of gonorrhea and not use it in the treatment of other infections.
Vecchio TJ. Resistance to Antibiotics By Gonococci. JAMA. 1972;220(1):128. doi:10.1001/jama.1972.03200010112031