Sickle cell anemia, hyperuricemia, and gout occurred in a 53-year-old woman. The hyperuricemia is felt to be the result of the increased erythropoiesis of sickle cell disease. This concept is supported by the finding of a significant incidence of hyperuricemia in other patients with sickle hemoglobinopathies.
Gold MS, Williams JC, Spivack M, Grann V. Sickle Cell Anemia and Hyperuricemia. JAMA. 1968;206(7):1572-1573. doi:10.1001/jama.1968.03150070110030