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December 16, 1968

Depression of Poison Ivy Skin Tests by Measles Vaccine

Author Affiliations

From the Department of Medicine (Dr. Blumhardt), Allergy Service (Dr. Pappano), and Dermatology Service (Dr. Moyer), Madigan General Hospital, Tacoma, Wash. Dr. Blumhardt is now at the US Army Hospital, Ft Carson, Colo.

JAMA. 1968;206(12):2739-2741. doi:10.1001/jama.1968.03150120073026

The degree of sensitivity to varying dilutions of a poison ivy antigen was established by patch tests in seven individuals. Administration of the live, attenuated measles virus vaccine (Schwarz) to this small group of subjects resulted in a temporary reduction of sensitivity, most marked (33% of control values) between the third and sixth weeks postimmunization. At nine weeks, the sensitivity was returning to preimmunization levels. Five control subjects showed no change in their degree of sensitivity.