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June 12, 1972

Total Body Perfusion

Author Affiliations

USAF Lackland AFB, Tex

JAMA. 1972;220(11):1495. doi:10.1001/jama.1972.03200110073022

To the Editor.—  Recently we published an article citing our initial experience with asanguineous hypothermic total body perfusion (total body washout or TBW) in the resuscitation of a patient dying of stage IV hepatic coma.1 The patient went on to die of Pseudomonas pneumonia which was present prior to the performance of the TBW. That partial success served to teach us to be more selective of future candidates and to make certain adjustments in our perfusate. These were done in our latest attempt to use the procedure in the care of a young airman dying of acute Australia antigen hepatitis.The airman had been ill and hospitalized for four weeks prior to transfer to our hospital. In the fifth week of his illness and in spite of intensive therapy with bowel antisepsis, steroids, and modified diet, he lapsed into a deepening coma. When received at our hospital, the patient