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June 12, 1972


Author Affiliations

Washington University School of Medicine St. Louis

JAMA. 1972;220(11):1502. doi:10.1001/jama.1972.03200110080035

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For years the teaching of immunology in medical school curricula has been incorporated in the course of microbiology, since immunology in that era involved primarily a study of antibodies to infectious agents and anaphylaxis to foreign sera. During the past generation, however, the newer knowledge of the dynamics of the immune response and the delineation of immune globulins by immunoelectrophoresis, with the demonstrations of protective antibodies in IgG and reagins in IgE has established immunology as an autonomous subject rather than just a part of microbiology. Without losing sight of historical basic principles, the authors have presented the newer concepts of immunology and their clinical applications in this excellent book.

The book includes a fascinating introductory chapter of Ehrlich's and Metchnikoff's humoral and cellular theories of antibodies. Subsequent chapters include detailed descriptions of the physical, chemical, and biologic properties of "immunogens" (the term preferred by the author over "antigens") and