[Skip to Content]
[Skip to Content Landing]
January 20, 1969

Mumps Meningoencephalitis in Children

Author Affiliations

From the departments of pediatrics and medical microbiology, Ohio State University College of Medicine, and the Children's Hospital Research Foundation, Columbus, Ohio.

JAMA. 1969;207(3):509-512. doi:10.1001/jama.1969.03150160021004

Fifty-one children with mumps meningoencephalitis were studied. The disease occurred throughout the year, with higher frequency in boys. The disease was of short duration and was generally benign. Parotitis accompanied meningoencephalitis in 47% of the patients. Appropriate serologic studies and/or recovery of virus from cerebrospinal fluid, saliva, urine, or washings of throat swabs are essential for the diagnosis of mumps meningoencephalitis in the absence of parotitis. All children recovered uneventfully and follow-up examinations of 33 children 4 to 40 months after the onset of meningoencephalitis showed no neurological sequelae or hearing loss. Serum amylase concentration was found to be elevated in the presence of parotitis and generally normal in primary mumps meningoencephalitis.