Determination of ABO and HL-A antigens and sex ratio of infants born to 46 women with preeclampsia or eclampsia, in comparison with normal controls, disclosed no predominant blood group, HL-A haplotype, or qualitative difference in maternal-fetal incompatibility. These results suggest that a link between immunologic mechanisms and the pathogenesis of toxemia syndromes, if present at all, must be associated with feto-placental tissue-specific antigens.
(JAMA 235:402-404, 1976)
Scott JR, Beer AE, Stastny P. Immunogenetic Factors in Preeclampsia and EclampsiaErythrocyte, Histocompatibility, and Y-Dependent Antigens. JAMA. 1976;235(4):402-404. doi:10.1001/jama.1976.03260300028025