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February 9, 1976

Molecular Pathology

Author Affiliations

Temple University Health Sciences Center Philadelphia

JAMA. 1976;235(6):656. doi:10.1001/jama.1976.03260320062037

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This is a multiauthored book that consists of 31 chapters ranging from such general topics as the molecular basis of disease, to more specialized topics such as the testicular feminization syndrome. As is almost unavoidable with this type of book, the quality is quite uneven, some chapters being excellent indeed and others rather less attractive. Overall, however, the book contains a considerable amount of useful information and makes a gallant attempt to give molecular basis to pathology.

There are some chapters that I would like to single out for their particular excellence, including the one by Uitto and Prockop on the molecular defects in collagen and the definition of collagen diseases, the chapter on xeroderma pigmentosum by Setlow, and the one by Smuckler on "The Biochemical Basis of Acute Liver Cell Injury." Other readers may find other chapters more appealing, but as a general conclusion, I believe this volume could