A woman who had onset of pernicious anemia in adulthood subsequently manifested idiopathic hypoparathyroidism. No previous instances of the combination of these two diseases occurring in adults have been reported in detail. Circulating autoantibodies to thyroid microsomes, all three cellular zones of the adrenal cortex and Castle's intrinsic factor (both blocking and precipitating) were demonstrated in the serum of this patient. Periodic assessment of the endocrine status of patients with pernicious anemia should be considered.
Comin DB, Hines JD, Wieland RG. Coexistent Pernicious Anemia and Idiopathic Hypoparathyroidism in a Woman. JAMA. 1969;207(6):1147–1149. doi:10.1001/jama.1969.03150190069021