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August 14, 1972

Tenderness Above Parathyroid Adenoma

Author Affiliations

Brooklyn, NY

JAMA. 1972;221(7):716. doi:10.1001/jama.1972.03200200062032

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To the Editor.—  A preoperative finding that I have noted in five patients with primary hyperparathyroidism is that of marked tenderness in the region of the hyperfunctioning tumor.At neck exploration, each of these patients later proved to have a single parathyroid adenoma associated with edema of the surrounding tissues and with increased vascularity of the tumor itself.The reason for the tenderness is not known, but may be related to pressure on the parathyroid capsule and also to some local inflammatory response.Since the precise preoperative diagnosis of primary hyperparathyroidism is usually uncertain, the above finding should routinely be looked for. Its presence will reassure the surgeon and help localize the hyperfunctioning adenoma.