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August 21, 1972

Ischemic Myopathy in Uremic Hyperparathyroidism

Author Affiliations

From the departments of pathology (Drs. Goodhue and Porro) and neurology (Dr. Davis), New York Hospital-Cornell Medical Center, New York.

JAMA. 1972;221(8):911-912. doi:10.1001/jama.1972.03200210055015

Proximal, painful myopathy during life and complicating hyperparathyroidism secondary to chronic renal failure has been documented histologically only once previously. This patient's unusual, noninflammatory myopathy, with focal calcium deposits, was due to ischemia caused by luminal stenosis in arterioles with circumferential medial calcification and concentric fibrous intimal proliferation.