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March 3, 1969

Cytomegalovirus Infection After Renal TransplantationReport of a Case With Viremia and Atypical Lymphocytosis

Author Affiliations

From the departments of medicine and pediatrics, Memorial Hospital and Division of Immunology, Sloan-Kettering Institute; the Department of Biochemistry, the New York Hospital; and Cornell University Medical College, New York.

JAMA. 1969;207(9):1712-1714. doi:10.1001/jama.1969.03150220128023

"Cytomegalovirus (CMV) mononucleosis" developed in one patient after renal transplantation. The virus was isolated from the patient's blood on two occasions, one month apart, during the period of atypical lymphocytosis. High antibody titers subsequently developed, and CMV appeared in the urine and saliva, while the blood became negative. It is possible that the transplanted kidney was the source of the infecting CMV, in addition to transfused blood or exacerbation of a latent infection.