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March 22, 1976

Renal Tubular Dysfunction Secondary to Jejunoileal Bypass

Author Affiliations

From the University of Health Sciences, Chicago Medical School, Chicago (Dr Vainder), and St Francis Hospital, Evanston, III (Dr Kelly).

JAMA. 1976;235(12):1257-1258. doi:10.1001/jama.1976.03260380051029

HYPEROXALURIA as a sequel of jejunoileal bypass operation has been reported previously. We were, however, unable to find any reports of renal parenchymal deposition of oxalate with resultant tubular dysfunction. The following report describes such a case.

Report of a Case  A 51-year-old woman gave a long history of obesity characterized by multiple abortive attempts at weight reduction over the preceding 20 years. On Sept 11, 1966, a 61-and 25-cm jejunoileal shunt operation was performed. Her weight at that time was 140.5 kg. No biochemical abnormalities were noted, and the only incidental pathological finding was the presence of cholelithiasis. The patient was given various supplements including vitamins, calcium, and potassium postoperatively. She lost approximately 50 kg over the next year, and for five additional years stabilized at 90.5 kg.In November 1972, an elective cholecystectomy was performed for the relief of recurrent episodes of right-upper-quadrant pain. A revision of the