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October 9, 1972

Ureteral Dynamics: Pathophysiology, Drugs, and Surgical Implications

Author Affiliations

University of California San Francisco


by Saul Boyarsky and Peregrina C. Labay, 493 pp, with illus, $16.50, Williams & Wilkins Co., 1972.

JAMA. 1972;222(2):213-214. doi:10.1001/jama.1972.03210020059025

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This compendium of the excellent experimental work of Boyarsky and his associates over 20 years presents in minute detail the methods and results of experimental studies on the ureter.

After a detailed description and critical examination of methods used for study of ureteral activity, the authors cover the basic physiologic mechanisms involved. Their interest in the effects of drugs and n eurohormones is evident in subsequent chapters, where details of neurohistochemistry, pharmacology, and endocrinology are developed from the authors' own experiments. Finally, an attempt is made to relate the findings to clinical problems of diagnosis and solution of pathophysiologic problems.

The authors have long felt that mechanisms other than simple stretch account for ureteral peristalsis and proceed to document their experimental findings of trigger zones, nerve pathways, and drugs that act on myoneural junctions.

Much of the work has already been published by the authors; perhaps specific references to their