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April 19, 1976

Medical News

JAMA. 1976;235(16):1651-1662. doi:10.1001/jama.1976.03260420003001

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Biosynthetic eardrum reported ready to undergo clinical trial  A biosynthetic tympanic membrane prosthesis has been developed by California researchers and now is ready for clinical trials, according to Rodney Perkins, MD, who described it at a Chicago meeting.The tympanic membrane graft utilizes a new method of reconstituting collagen from mammalian sources into membranes with predictable physical characteristics. It appears that the process could be a forerunner for other types of prepared bioimplant prostheses for surgical reconstructive procedures in other speciality fields.Dr Perkins is research director of Project Hear, a nonprofit medical foundation in Palo Alto, and is on the clinical faculty of Stanford University Medical Center. He spoke at the Shambaugh Fifth International Workshop on Middle Ear Microsurgery and Fluctuant Hearing Loss at Northwestern University.The concept of a biosynthetic eardrum of reconstituted collagen developed during the late 1960s, according to Dr Perkins."We at Project Hear