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November 20, 1972

Cardiomyopathy: Presenting Symptom of Progressive Muscular Dystrophy

Author Affiliations

Louis A. Weiss Memorial Hospital University of Illinois Chicago

JAMA. 1972;222(8):1060. doi:10.1001/jama.1972.03210080140031

To the Editor.—  The heredofamilial myopathic disorders, progressive muscular dystrophy and dystrophia myotonica, are frequently complicated by cardiomyopathy.1,2 Perloff et al described diagnostic electrocardiographic patterns for these conditions in an excellent review that included a detailed prospective study of cardiomyopathy in a variety of dystrophic types.3 Nonetheless, cardiac expression in muscular dystrophy often occurs late in the disease, and occult cardiac involvement frequently goes unrecognized.4This report describes a case of progressive muscular dystrophy in which the initial major clinical manifestation was cardiomyopathy.

Report of a Case.—  The patient, a 22-year-old white man, was an only child. His birth and developmental history were normal. His history revealed no serious illness, and there was no family history of neuromuscular disease. He did not smoke or drink alcohol. He had never been athletic, and late in adolescence he noticed mild weakness when ascending stairs and moderate fatigue after vigorous