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December 4, 1972

Current Status of Lymphography

JAMA. 1972;222(10):1299-1301. doi:10.1001/jama.1972.03210100047016

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Characteristic findings in Hodgkin's disease are the lacunar patterns (micro lacunary and macrolacunary defects) that are seen as punched out, rounded, small, or large filling defects in the nodes.51-53 Minimal distortion of nodal architecture and normal or minimally disturbed contour of the nodes are frequent findings. Pelvic and para-aortic node involvement by Hodgkin's disease may occur histologically, despite the normality of the adenographic pattern by lymphography. In some types of Hodgkin's disease with diffuse fibrosis, the lymph node architecture may not be recognized because of total replacement of the lymph nodes by disease. Nonspecific enlargement of otherwise normallooking lymph nodes, and coarse reticular pattern may be observed occasionally. Increased numbers of nodes are seen often in infants and children.

There are no adenographic patterns pathognomonic of Hodgkin's disease.53 Total replacement of nodal architecture can be seen with diffuse metastatic disease following retroperitoneal adenectomy, and in patients with retroperitoneal