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May 31, 1976

Wernicke Encephalopathy Following Prolonged Intravenous Therapy

Author Affiliations

From the departments of neurology and pathology, Duke University Medical Center, Durham, NC.

JAMA. 1976;235(22):2403-2405. doi:10.1001/jama.1976.03260480023023

Two nonalcoholic patients who were maintained for extended periods on intravenous fluids manifested the morphologic expressions of Wernicke encephalopathy. A thiamine-deficiency state was not suspected and vitamins were never administered. These cases emphasize the consequences of this disorder and the rapidity with which the state of thiamine depletion can develop.

(JAMA 235:2403-2405, 1976)