Two nonalcoholic patients who were maintained for extended periods on intravenous fluids manifested the morphologic expressions of Wernicke encephalopathy. A thiamine-deficiency state was not suspected and vitamins were never administered. These cases emphasize the consequences of this disorder and the rapidity with which the state of thiamine depletion can develop.
(JAMA 235:2403-2405, 1976)
Nadel AM, Burger PC. Wernicke Encephalopathy Following Prolonged Intravenous Therapy. JAMA. 1976;235(22):2403-2405. doi:10.1001/jama.1976.03260480023023