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June 21, 1976

Studies of the Hypothalamus and the Pitultary Gland: With Special Reference to the Effects of Transection of the Pituitary Stalk

Author Affiliations

The University of British Columbia Vancouver

JAMA. 1976;235(25):2771. doi:10.1001/jama.1976.03260510059038

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In a difficult field, the present volume offers a superb summary of the findings of two senior researchers who worked for 25 years at the Nuffield Institute for Medical Research at Oxford, and in the Department of Neuropathology at the University of London. The illustrations alone could carry the story, so exceptional are they.

The work has the additional merit of dealing with normal and pathological states in a wide variety of animals as well as in humans. The techniques used to trace the two groups of portal vessels (not a single system as we once thought) are highly refined in the hands of two veterans schooled in the intricacies of vascular shunts. The cytological changes following interruption of the stalk are well documented, but a surprising thing is the wealth of regenerating nerve fibers to be found some time after the hypthalamo-hypophysial tract has been cut.

A good bibliography