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January 22, 1973

Intravenous Hyperalimentation

Author Affiliations

Veterans Administration Center Togus, Me

JAMA. 1973;223(4):441. doi:10.1001/jama.1973.03220040055024

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To the Editor.—  In Dr. Shils's summary of recent advances in parenteral nutrition authorized by the Council on Food and Drugs (220:1721, 1972), it is mentioned that the first use of the term "hyperalimentation" appeared in the clinical literature in 1965 and referred to supplementary feedings of intravenous fat. The term actually was first used by CoTui in 1945 to describe the administration of large amounts of protein hydrolysates and Dextri-Maltose by mouth in order to completely buffer gastric acidity. In the belief that the acidbuffering effect of food given by mouth was less important in the treatment of patients with peptic ulcer than the necessity of giving depleted individuals adequate calories and protein, in 1952 I started feeding large quantities of protein hydrolysates by vein to such patients with peptic ulcer. I called this procedure "intravenous hyperalimentation," as I recommended that more protein than the 1 gm/1 kg of