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February 12, 1973

Immunofluorescent Test for Lupus Erythematosus: Relation to Renal Disease

Author Affiliations

Henry Ford Hospital Detroit

JAMA. 1973;223(7):798-799. doi:10.1001/jama.1973.03220070052019

To the Editor.—  In the recent report by Caperton et al (222:935, 1972), no correlation was found between the incidence of renal disease and a positive immunofluorescent "band" test in clinically normal skin from patients with systemic lupus erythematosus (SLE).The authors obtained clinically normal results for skin tests from the back of the upper arm or from over the scapula. Both these sites usually represent light-exposed skin. Baart de la Faille-Kuyper and Cormane already reported in 1968 that the band was found much more frequently in light-exposed clinically normal skin with lupus erythematosus than in skin obtained from usually light-protected areas.1 Fifteen of 15 patients with lupus erythematosus (100%), demonstrated a band in light-exposed uninvolved skin taken from the extensor surface of the forearm, whereas only four of these patients (26.6%) showed a band in skin obtained from clinically normal skin from the back at light-protected sites.1 We