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February 19, 1973

Hypogeusia, Anorexia, and Altered Zinc Metabolism Following Thermal Burn

Author Affiliations

From the Experimental Therapeutics Branch, National Heart and Lung Institute, National Institutes of Health, Bethesda, Md. Dr. Cohen is now with the Department of Surgery, Medical College of Virginia, Richmond.

JAMA. 1973;223(8):914-916. doi:10.1001/jama.1973.03220080044013

Taste acuity and zinc and copper metabolism were studied in 19 patients with thermal burns. Eighty-four percent exhibited hypogeusia (decreased taste acuity). Mean serum total zinc concentration was decreased and mean urinary zinc excretion was increased in the patients with hypogeusia compared to controls. An association among hypogeusia, anorexia, and altered zinc metabolism after thermal injury is strongly suggested.