[Skip to Content]
[Skip to Content Landing]
March 5, 1973

Reversal of Myelofibrosis in Hodgkin Disease

Author Affiliations

From the departments of medicine (Drs. Viola and Nukhopadhyay) and pathology (Dr. Kovi), Howard University School of Medicine, Washington, DC.

JAMA. 1973;223(10):1145-1146. doi:10.1001/jama.1973.03220100041009

A 31-year-old woman had Hodgkin disease associated with extensive myelofibrosis. Peripheral-blood examination revealed pancytopenia with circulating, immature white blood cells and abnormal red blood cell forms. Following four courses of quadruple chemotherapy the patient had a normal peripheral-blood picture, and a single bone marrow needle biopsy specimen was normal.