A 31-year-old woman had Hodgkin disease associated with extensive myelofibrosis. Peripheral-blood examination revealed pancytopenia with circulating, immature white blood cells and abnormal red blood cell forms. Following four courses of quadruple chemotherapy the patient had a normal peripheral-blood picture, and a single bone marrow needle biopsy specimen was normal.
Viola MV, Kovi J, Nukhopadhyay M. Reversal of Myelofibrosis in Hodgkin Disease. JAMA. 1973;223(10):1145–1146. doi:10.1001/jama.1973.03220100041009