Hypomagnesemia uncomplicated by other factors can give rise to an organic brain syndrome. In a patient with bleeding peptic ulcer, hypomagnesemia occurred secondary to intravenous fluid replacement and suction losses. The patient developed cramping, nystagmus, tremor, clonus, myoclonic jerks, hyperacusia, Chvostik sign, hypertension, tachycardia, and an acute organic brain syndrome. Cerebrospinal fluid and serum magnesium concentrations can be correlated to the treatment schedule, symptom progression, and electroencephalographic changes.
Hall RCW, Joffe JR. HypomagnesemiaPhysical and Psychiatric Symptoms. JAMA. 1973;224(13):1749–1751. doi:10.1001/jama.1973.03220270045012