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June 25, 1973

HypomagnesemiaPhysical and Psychiatric Symptoms

Author Affiliations

From the University of South Florida College of Medicine, Tampa (Dr. Hall), the US Naval Hospital, Orlando, Fla (Dr. Hall), and the Johns Hopkins University College of Medicine, Baltimore (Dr. Joffe).

JAMA. 1973;224(13):1749-1751. doi:10.1001/jama.1973.03220270045012

Hypomagnesemia uncomplicated by other factors can give rise to an organic brain syndrome. In a patient with bleeding peptic ulcer, hypomagnesemia occurred secondary to intravenous fluid replacement and suction losses. The patient developed cramping, nystagmus, tremor, clonus, myoclonic jerks, hyperacusia, Chvostik sign, hypertension, tachycardia, and an acute organic brain syndrome. Cerebrospinal fluid and serum magnesium concentrations can be correlated to the treatment schedule, symptom progression, and electroencephalographic changes.