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October 18, 1976

Osteosclerotic Myeloma

Author Affiliations

From the Hematology Section, Department of Medicine, Medical College of Georgia, Augusta (Drs Rodriguez and Lutcher); and Valdosta, Ga (Dr Coleman).

JAMA. 1976;236(16):1872-1874. doi:10.1001/jama.1976.03270170038023

A 49-year-old man with an osteosclerotic lesion of a thoracic vertebra had peripheral neuropathy, lymphadenopathy, and elevated serum alkaline phosphatase and monoclonal immunoglobulin levels in the cerebrospinal fluid. These findings, not usually seen in "classical" myeloma, have been noted in different combinations in the osteosclerotic variety.

(JAMA 236:1872-1874, 1976)